Tyrosols and derivatives
Selleck Chemical LLC VX-702
VX-702 is a highly selective inhibitor of p38 MAPK 14-fold higher potency against the p38 versus p38
Medchemexpress LLC VX-702 | 745833-23-2 | 99.7% | 404.32 | 25 MG
VX-702 is a highly selective inhibitor of p38α MAPK, demonstrating 14-fold higher potency against p38α compared to p38β. It is intended for research use only and not for patient use.
- Highly selective p38α MAPK inhibitor, exhibiting 14-fold higher potency against p38α than p38β.
- Inhibits p38 activation in platelets at 1 μM concentration.
- No effect on platelet aggregation induced by p38 MAPK agonists.
- Inhibits cytokine production of IL-6, IL-1β, and TNFα.
- Long half-life of 16 to 20 hours in vivo.
- Predominantly cleared renally.
- Comparable efficacy to methotrexate and prednisolone in inhibiting wrist joint erosion and inflammation.
Medchemexpress LLC (3,4-Dimethoxyphenyl)hydrazine hydrochloride | 40119-17-3 | 204.66 | 5 G
(3,4-Dimethoxyphenyl)hydrazine hydrochloride serves as a drug intermediate for the synthesis of various active compounds. This chemical is suitable for research applications.
- Used as a drug intermediate
- Purity of 99.8%
- Appears as a solid
- Color is light brown to gray
Medchemexpress LLC 4-Methoxyphenethyl alcohol | 702-23-8 | 152.19 | 50 G
4-Methoxyphenethyl alcohol is an aromatic alcohol, identified as a major component of the anise-like odor produced by Amorphophallus. It inhibits protein, RNA, and DNA synthesis, demonstrating a complete bacteriostatic concentration of 4.8 mM against Escherichia coli.
- Aromatic alcohol
- Major component of anise-like odor
- Inhibits protein, RNA, and DNA synthesis
- Bacteriostatic against Escherichia coli at 4.8 mM
Medchemexpress LLC (3,4-Dimethoxyphenyl)hydrazine hydrochloride | 40119-17-3 | 204.66 | 100 MG
(3,4-Dimethoxyphenyl)hydrazine hydrochloride is a drug intermediate used for the synthesis of various active compounds.
- Used for the synthesis of various active compounds
- Purity 99.84%
- Molecular weight 204.66
- Appearance: solid
- Color: light brown to gray
Apexbio Technology LLC VX-702 479543-46-9; 745833-23-2 50mg
VX-702 is a small-molecule inhibitor targeting p38 mitogen-activated protein kinase (MAPK) also known as MAPK14 It is designed to inhibit p38 MAPK thereby regulating cellular responses to cytokine signaling and various stressors VX-702 exerts its biological activity primarily through ATP-competitive inhibition In experimental models VX-702 demonstrates potent inhibition with reported IC50 values ranging from 4 to 20 nM Based on these pharmacological properties VX-702 holds research potential in the study of p38 MAPK-dependent pathways platelet storage lesions and renal excretion mechanisms
Medchemexpress LLC 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide | 745833-23-2 | MFCD11616590 | 99.7% | 404.32 g/mol | C19H12F4N4O2 | 1 ML
VX-702 is a selective small-molecule inhibitor of p38α mitogen-activated protein kinase (MAPK) used in research to probe p38α-mediated signaling and inflammatory pathways. It demonstrates higher potency for p38α than p38β and has been evaluated in preclinical and clinical studies for anti-inflammatory applications. Supplied for laboratory research use only.
- Selective p38α MAPK inhibitor with approximately 14-fold selectivity over p38β.
- Suitable for studying inflammatory signaling and cytokine regulation.
- Provided as a 10 mM solution in DMSO for ready-to-use applications.
- High purity (product page lists 99.69%), appropriate for biochemical assays.
- Molecular weight 404.32 g/mol and formula C19H12F4N4O2.
- Good solubility in DMSO (≥ 42 mg/mL) for convenient stock preparation.
- For research use only; not intended for human or veterinary use.
Medchemexpress LLC 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide | 745833-23-2 | MFCD11616590 | 99.7% | 404.32 g/mol | C19H12F4N4O2 | 100 MG
VX-702 is a small-molecule research inhibitor selective for the p38α isoform of mitogen-activated protein kinase (MAPK). It is used to probe MAPK signaling and inflammatory cytokine production in preclinical and cellular studies. The compound is supplied as a powder with high reported purity and documented potency against p38α.
Selleck Chemical LLC Verbascoside S5458-5mg
Verbascoside (Acteoside Kusaginin) a phenylpropanoid glycoside from lemon verbena has several biological properties such as anti-inflammatory antimicrobial antitumor and antioxidant
Medchemexpress LLC Abt-702 dihydrochloride | 1188890-28-9 | 99.8% | 536.25 g/mol | C22H21BrCl2N6O | 100 MG
ABT-702 dihydrochloride is a potent, non-nucleoside adenosine kinase (AK) inhibitor (IC50 = 1.7 nM), supplied as the dihydrochloride salt for research use. It is used in biochemical and cellular studies to modulate adenosine kinase activity.
- Potent adenosine kinase inhibitor with IC50 = 1.7 nM.
- Dihydrochloride salt form for improved stability and solubility.
- Molecular formula C22H21BrCl2N6O; molecular weight 536.25 g/mol.
- Intended for research use in biochemical and cellular assays.
- Store sealed away from moisture; in solvent, -80°C (up to 6 months) or -20°C (up to 1 month).
Apexbio Technology LLC VX-702 479543-46-9; 745833-23-2 10mM (in 1mL DMSO)
VX-702 is a small-molecule inhibitor targeting p38 mitogen-activated protein kinase (MAPK) also known as MAPK14 It is designed to inhibit p38 MAPK thereby regulating cellular responses to cytokine signaling and various stressors VX-702 exerts its biological activity primarily through ATP-competitive inhibition In experimental models VX-702 demonstrates potent inhibition with reported IC50 values ranging from 4 to 20 nM Based on these pharmacological properties VX-702 holds research potential in the study of p38 MAPK-dependent pathways platelet storage lesions and renal excretion mechanisms
Chemscene ChemScene | Hydroxytyrosol | 1G | CS-0009107 | 0.98 | 10597-60-1| MFCD01320529 | 154.16
ChemScene | Hydroxytyrosol | 1G | CS-0009107 | 0.98 | 10597-60-1| MFCD01320529 | 154.16
Medchemexpress LLC VX-702 50mg | 745833-23-2 | 50MG
VX-702 is a highly selective inhibitor of p38 MAPK 14-fold higher potency against the p38 versus p38 [1
